Lipedema has unique features that set it apart from obesity, lymphedema, and general weight gain.

Common signs include:

• Painful or tender fat

• Easy bruising

• Heaviness in legs or arms

• Swelling that worsens throughout the day

• Fat buildup that does not respond to diet or exercise

• “Column-like” or “tree trunk” legs

• Nodules or a “grainy” texture under the skin

• Fat disproportion (legs/arms larger than torso)

• Feet and hands are not swollen (a major differentiator)